منابع مشابه
miR‑142‑3p promotes osteoblast differentiation by modulating Wnt signaling.
Canonical Wnt signaling is critical for the control of osteoblast differentiation in human mesenchymal stem cells. MicroRNAs (miRs) are essential regulators of cell differentiation by post‑transcriptional regulation of target gene expression. The aim of the present study was to investigate the molecular mechanism by which miR‑142‑3p promotes osteoblastic differentiation using the human fetal os...
متن کاملPhagocytosis in Myeloid Inflammatory Cells miR-24, miR-30b, and miR-142-3p Regulate
Micro-RNAs (miRNAs) are small noncoding RNAs that regulate various biological pathways. As their role in phagocytosis remains poorly understood, we investigated their impact on phagocytosis in myeloid inflammatory cells. Seven miRNAs (miR-24,-30b,-101, 142-3p,-652-3p,-652-5p, and-1275) that were differentially expressed during monocyte to macrophage (Mw) and monocyte to dendritic cell (DC) diff...
متن کاملAssociation of Serum MiR-142-3p and MiR-101-3p Levels with Acute Cellular Rejection after Heart Transplantation
BACKGROUND Identifying non-invasive and reliable blood-derived biomarkers for early detection of acute cellular rejection in heart transplant recipients is of great importance in clinical practice. MicroRNAs are small molecules found to be stable in serum and their expression patterns reflect both physiological and underlying pathological conditions in human. METHODS We compared a group of he...
متن کاملDownregulation of Plasma MiR-142-3p and MiR-26a-5p in Patients With Colorectal Carcinoma
BACKGROUND Colorectal cancer is one of the most commonly diagnosed cancers and cancer- related death worldwide. Identification of new specific biomarkers could be helpful to detection of this malignancy. Altered plasma microRNA expression has been identified in many cancers, including colorectal cancer. OBJECTIVES The main objective of this study was to identify the circulating microRNAs with...
متن کاملmiR-24, miR-30b and miR-142-3p interfere with antigen processing and presentation by primary macrophages and dendritic cells
Antigen uptake, processing and presentation by antigen presenting cells (APCs) are tightly coupled processes which consequently lead to the activation of innate and adaptive immune responses. However, the regulatory role of microRNA (miRNAs) in these critical pathways is poorly understood. In this study, we show that overexpression of miR-24, miR-30b and miR-142-3p attenuates uptake and process...
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ژورنال
عنوان ژورنال: médecine/sciences
سال: 2013
ISSN: 0767-0974,1958-5381
DOI: 10.1051/medsci/2013296007